: any of numerous compounds characterized by a 5-membered ring containing at least one nitrogen atom
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At the same time that medicine was benefiting from the new class of azole drugs, agriculture had been using a class of fungicides based on the same chemical structure.—Maryn McKenna, Scientific American, 13 Feb. 2025 Brexafemme is priced at a substantial premium compared to older azole treatment options, such as fluconazole.—Joshua Cohen, Forbes, 6 July 2022 In the Texas outbreak, in addition to the two pan-resistant cases, there were five patients with C. auris that was resistant to both echinocandins and fluconazole, an antifungal drug in the azole class.—Helen Branswell, STAT, 22 July 2021 And there are other problems: Only one class of drugs, the azoles, can be taken orally.—Kai Kupferschmidt, Science | AAAS, 22 Oct. 2019 More than 90 percent were resistant to azoles; 30 percent were resistant to the class that contains amphotericin; and globally, up to 20 percent were resistant to the last-ditch echinocandins.—Maryn McKenna, WIRED, 13 July 2018