antiandrogen

noun

an·​ti·​an·​dro·​gen ˌan-tē-ˈan-drə-jən 

ˌan-ˌtī-

variants or anti-androgen

plural antiandrogens or anti-androgens

: a substance (such as cyproterone) that tends to inhibit the production, activity, or effects of testosterone and other male sex hormones

… men with regional or metastatic disease are probably included in the analysis as suggested by the statistically different survival curves for men receiving immediate vs delayed antiandrogen therapy.

—P. C. Albertsen et al.

antiandrogenic

ˌan-tē-ˌan-​drə-​ˈje-​nik 

ˌan-ˌtī-

adjective

or anti-androgenic

Many commercial chemicals possess antiandrogenic activity.

—J. Raloff

Examples of antiandrogen in a Sentence

Recent Examples on the Web

Transgender women usually take antiandrogens with estrogen (or castration) to reduce the effects of androgens such as testosterone and induce feminization. —New Atlas, 31 July 2025

Additionally, after suffering a bad bout of adult acne, I was prescribed an antiandrogen called spironolactone. —Sam Reed, Glamour, 11 Apr. 2025

The effects of spironolactone on females for hair loss are mediated through the drug’s antiandrogen effects. —Mary Choy, Verywell Health, 6 Mar. 2025

May Reduce Testosterone Levels Some evidence suggests that spearmint may have antiandrogen properties. —Jillian Kubala, Health, 19 Jan. 2025

And Rettig says his team is now conducting an interim analysis of trial results on degarelix, another antiandrogen. —Robert F. Service, Science | AAAS, 7 July 2021

Word History

First Known Use

1961, in the meaning defined above

Medical Definition

antiandrogen

noun

an·​ti·​an·​dro·​gen -ˈan-drə-jən 

: a substance that tends to inhibit the production, activity, or effects of a male sex hormone

antiandrogenic

-ˌan-drə-ˈjen-ik 

adjective