Definition of anole
: any of a genus (Anolis) of arboreal American lizards (such as the American chameleon) of the iguana family that have a brightly colored dewlap and the ability to change color
Origin and Etymology of anole
probably from French anolis, from Arawak of the Lesser Antilles
First Known Use: 1745
Seen and Heard
What made you want to look up anole? Please tell us where you read or heard it (including the quote, if possible).