animal model

noun

: an animal sufficiently like humans in its anatomy, physiology, or response to a pathogen to be used in medical research in order to obtain results that can be extrapolated to human medicine
also : a pathological or physiological condition that occurs in such an animal and is similar to one occurring in humans

Example Sentences

Recent Examples on the Web One of the main obstacles in research and drug development for NF1 was the lack of a large animal model that can reliably allow scientists to predict whether drugs that work in animals might also be effective in people. Amy Dockser Marcus, WSJ, 6 Sep. 2022 There has been no suitable animal model for studying the disease until recently, adding to the challenges in understanding the virus. William A. Haseltine, Forbes, 3 June 2022 The researchers found that supplementing a diet with sea squirts, more formally called Ascidiacea, can reverse the signs of aging in an animal model. Joshua Hawkins, BGR, 22 May 2022 But Glanville, then the chief executive officer of a tiny San Francisco company called Distributed Bio, has made significant progress, successfully creating an antibody that neutralizes the coronavirus in hamsters, an animal model for humans. Kyle Dickman, Outside Online, 4 Mar. 2021 There is increasing data in animal model experiments that reducing the number of senescent cells via pharmacological or genetic approaches can reverse these physiological deficits and even extend lifespan. Gabriel A. Silva, Forbes, 1 Feb. 2022 Scientists had pinpointed mink as a likely animal model in which to study the pathogenesis of coronaviruses 16 years ago, in the wake of the first global SARS outbreak. New York Times, 19 Jan. 2022 The very first animal model of obesity set the precedent. Gary Taubes, STAT, 16 Sep. 2021 Today, this is known as an animal model of the disease. James P. Brody, The Conversation, 21 July 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'animal model.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

Word History

First Known Use

1955, in the meaning defined above

Time Traveler
The first known use of animal model was in 1955

Dictionary Entries Near animal model

Cite this Entry

“Animal model.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/animal%20model. Accessed 27 Nov. 2022.

Medical Definition

animal model

noun

: an animal sufficiently like humans in its anatomy, physiology, or response to a pathogen to be used in medical research in order to obtain results that can be extrapolated to human medicine
also : a pathological or physiological condition that occurs in such an animal and is similar (as in its pathology or physiology) to a human condition
experimental allergic encephalomyelitis is a useful animal model in the study of multiple sclerosis in humans
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