anergy

noun an·er·gy \ ˈa-(ˌ)nər-jē \

Definition of anergy

:a condition in which the body fails to react to an antigen

Origin and Etymology of anergy

International Scientific Vocabulary 2a- + -ergy (as in allergy


Medical Dictionary

anergy

noun an·er·gy \ ˈan-(ˌ)ər-jē \

medical Definition of anergy

plural anergies
:a condition in which the body's immune system fails to react to an antigen :immunological hyporesponsiveness
  • Specific anergy is lack of reactivity to an individual antigen, while generalized (nonspecific) anergy is the inability to react to any antigen.
  • —Harriet Kitzman et al.The Journal of the American Medical Association19 Apr. 2000
  • By deliberately throwing cells into anergy, researchers also hope to control allergies and certain autoimmune diseases like rheumatoid arthritis, in which white blood cells attack the body's connective tissue in the joints.
  • —Gina KolataThe New York Times22 Oct. 1991

anergic

play \-jik\ adjective
    • If the second signal is not provided, the T cell becomes unresponsive (anergic).
    • —Suryaprakash R. Sambhara et al., Science, 7 June 1991
    • Patients with AIDS have tended to be anergic (both on skin tests and in vitro) and lymphopenic …
    • —D. Peter DrotmanThe Journal of the American Medical Association22 July 1983

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