am·​pli·​con | \ ˈam-plə-ˌkän How to pronounce amplicon (audio) \
plural amplicons

Definition of amplicon

: a segment of chromosomal DNA that undergoes amplification and contains replicated genetic material After PCR, the amplicon is captured by hybridization to a specific oligonucleotide probe, which increases the overall specificity of the test.— Benjamin T. Davis et al., New England Journal of Medicine, 19 Jan. 2006

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First Known Use of amplicon

1982, in the meaning defined above

History and Etymology for amplicon

ampli(fy) (in cloning-amplifying vector) + -icon (as in replicon)

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The first known use of amplicon was in 1982

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Cite this Entry

“Amplicon.” Dictionary, Merriam-Webster, Accessed 14 Jul. 2020.

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