aminopterin

noun
am·​i·​nop·​ter·​in | \ ˌa-mə-ˈnäp-tə-rən How to pronounce aminopterin (audio) \

Definition of aminopterin

: a derivative C19H20N8O5 of glutamic acid that is a folic acid antagonist and has been used as a rodenticide and antileukemic agent

Examples of aminopterin in a Sentence

Recent Examples on the Web In the late 1940s, legendary cancer researcher Sydney Farber and colleagues reported successfully treating acute leukemia in children with a new drug called aminopterin. Gwen Nichols, STAT, "Precision medicine has a blind spot: children with cancer," 30 Dec. 2019 In 1947 aminopterin, a chemical which messes up cell division by interrupting the metabolism of folic acid, was found to produce remissions in children with acute leukaemia. The Economist, "Knives, beams, drugs and antibodiesToday’s anti-cancer tools are ever better wielded," 14 Sep. 2017

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'aminopterin.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of aminopterin

1948, in the meaning defined above

History and Etymology for aminopterin

amino + pteroylglutamic acid + -in

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The first known use of aminopterin was in 1948

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Cite this Entry

“Aminopterin.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/aminopterin. Accessed 24 Oct. 2020.

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More Definitions for aminopterin

aminopterin

noun
am·​i·​nop·​ter·​in | \ ˌam-ə-ˈnäp-tə-rən How to pronounce aminopterin (audio) \

Medical Definition of aminopterin

: a derivative C19H20N8O5 of glutamic acid that is a folic acid antagonist and has been used as a rodenticide and antileukemic agent

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