Definition of allostatic load
: the cumulative adverse effect on the body when allostasis occurs too frequently (as when the body is subjected to repeated stressors) or is inadequate Over weeks, months, or years, exposure to increased secretion of stress hormones can result in allostatic load and its pathophysiologic consequences. — Bruce S. McEwen, New England Journal of Medicine, 15 Jan. 1998
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First Known Use of allostatic load
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