acet·​amin·​o·​phen | \ ə-ˌsē-tə-ˈmi-nə-fən How to pronounce acetaminophen (audio) , ˌa-sə-tə- \

Definition of acetaminophen

: a crystalline compound C8H9NO2 that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine to relieve pain and fever

Examples of acetaminophen in a Sentence

Recent Examples on the Web Long before the current opioid crisis, the scientific community and literature knew of the dangers of NSAIDs and acetaminophen (Tylenol). Scientific American, 1 Mar. 2022 Percocet, a combination of acetaminophen and oxycodone, was discovered in Skaggs’ hotel room, but it wasn’t discovered in his system, according to the autopsy report. Los Angeles Times, 15 Feb. 2022 Tylenol contains the active ingredient acetaminophen, and Advil contains the active ingredient ibuprofen. Serena Coady, SELF, 12 Feb. 2022 Percocet, an opioid, is a mixture of oxycodone and acetaminophen. Los Angeles Times, 14 Feb. 2022 The aspirin and acetaminophen tablets are still good to use. Chris Smith, BGR, 31 Jan. 2022 Fewer patients in the treatment group reported taking acetaminophen (Tylenol), but that was true even in the first week of the study, when the treatment and control groups were reporting practically identical levels of pain. Paul T. Von Hippel, STAT, 24 Jan. 2022 In the car, detectives later found a backpack on the driver’s floorboard with two bricks of heroin/fentanyl along with about 12 grams in powder form, about 161 grams of meth, several MDMA tablets and acetaminophen and oxycodone hydrochloride pills. Tiffini Theisen,, 14 Jan. 2022 Twenty-six of the mother and child studies found a link between acetaminophen exposure during pregnancy and neurodevelopmental outcomes, the statement noted. Sandee Lamotte, CNN, 23 Sep. 2021 See More

These example sentences are selected automatically from various online news sources to reflect current usage of the word 'acetaminophen.' Views expressed in the examples do not represent the opinion of Merriam-Webster or its editors. Send us feedback.

First Known Use of acetaminophen

1958, in the meaning defined above

History and Etymology for acetaminophen

acet(yl) + amino + phen(ol)

Note: Shortened from N-acetyl-p-aminophenol. Acetaminophen was introduced as a generic name roughly coincident with the introduction of the trademark preparation Tylenol, which was first marketed as "Children's Tylenol Elixir" in 1955 by McNeil Laboratories. Synthesis of the substance, as acetylamidophenol, was first reported in Berichte der Deutschen Chemischen Gesellschaft, 11. Jahrgang (Jan.-Juni, 1878), p. 232-33 (H. N. Morse, "Ueber eine neue Darstellungsmethode der Acetylamidophenole"). Its antipyretic properties were recognized by the German physician Josef von Mering in the 1893 article "Beiträge zur Kenntniss der Antipyretica" (Therapeutische Monatshefte, 7, pp. 577-87)—he also refers to it as acetylamidophenol.

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The first known use of acetaminophen was in 1958

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Cite this Entry

“Acetaminophen.” Dictionary, Merriam-Webster, Accessed 26 Jun. 2022.

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More Definitions for acetaminophen


acet·​amin·​o·​phen | \ ə-ˌsēt-ə-ˈmin-ə-fən How to pronounce acetaminophen (audio) , ˌas-ət- How to pronounce acetaminophen (audio) \

Medical Definition of acetaminophen

: a crystalline compound C8H9NO2 that is a hydroxy derivative of acetanilide and is used in chemical synthesis and in medicine instead of aspirin to relieve pain and fever

called also paracetamol

— see liquiprin, panadol, tylenol

More from Merriam-Webster on acetaminophen

Nglish: Translation of acetaminophen for Spanish Speakers Encyclopedia article about acetaminophen


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