: a variant DNA sequence in which the purine or pyrimidine base (such as cytosine) of a single nucleotide has been replaced by another such base (such as thymine)

Examples of SNP in a Sentence

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Murrell’s plea capped a five-year police investigation of the SNP, which has led Scotland’s semiautonomous government for almost two decades while campaigning for the country to break away from the United Kingdom. ABC News, 31 May 2026 The governing Scottish National Party (SNP) lost two seats in the Scottish Parliament, and in Wales, separatist Plaid Cymru for the first time captured a plurality of the seats in the Senedd Cymru or Welsh Parliament. Arthur I. Cyr, Chicago Tribune, 12 May 2026 Faced with widespread antipathy, those mainstream forces have been hammered by the electorate, with voters increasingly turning to the Greens and Reform, as well as Plaid and the SNP in Wales and Scotland. Alexander Smith, NBC news, 8 May 2026 An additional bone sample helped produce a Single Nucleotide Polymorphism (SNP) DNA profile. Daniel S. Levine, PEOPLE, 6 May 2026 Those without it need the direct-to-consumer option, SNP 360. Steven Louis Goldstein, New York Times, 17 Mar. 2026 As a result, SNP sequencing is more effective on degraded or incomplete samples. Michael Ruiz, FOXNews.com, 23 Feb. 2026 Humana is also a Dual Eligible Special Needs HMO SNP, PPO SNP plan with a Medicare contract and a contract with the state Medicaid program. Miami Herald, 6 Nov. 2025 May Humza Yousaf announces his resignation as First Minister of Scotland, paving the way for the SNP's second leadership contest in less than 14 months. The Week Uk, theweek, 25 Dec. 2024

Word History

Etymology

single nucleotide polymorphism

First Known Use

1991, in the meaning defined above

Time Traveler
The first known use of SNP was in 1991

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Cite this Entry

“SNP.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/SNP. Accessed 7 Jun. 2026.

Medical Definition

SNP

noun
: a variant DNA sequence in which the purine or pyrimidine base (as cytosine) of a single nucleotide has been replaced by another such base (as thymine)
Most SNPs occur in places in the genome that aren't used for making proteins—the so-called junk DNA. But the few SNPs that land squarely in a gene or in a regulatory region near a gene can alter characteristics influenced by that gene …Christen Brownlee, Science News
The ultimate goal of the pharmaceutical industry is to find the SNPs involved with major diseases and use them to find specific molecular targets for drugs.Tim Friend, USA Today

called also single nucleotide polymorphism

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