: a variant DNA sequence in which the purine or pyrimidine base (such as cytosine) of a single nucleotide has been replaced by another such base (such as thymine)

Examples of SNP in a Sentence

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Pittsburgh Pirates games will be televised on the RSN SportsNet Pittsburgh (SNP). Brad Adgate, Forbes, 4 Mar. 2025 Some British politicians, including the leader of the Scottish National Party (SNP), have called for the offer to be withdrawn after Trump accused Zelenskyy of not being grateful enough for U.S. support in Ukraine's war. Andrew MacAskill and Kate Holton, USA TODAY, 2 Mar. 2025 His departure was precipitated by his decision to tear up a power- sharing deal with the SNP's junior coalition partner, the Scottish Greens, who promptly responded by backing a vote of no confidence in him. The Week Uk, theweek, 25 Dec. 2024 Meanwhile, the Scottish National Party, or SNP, had a disastrous night, suffering a near total wipeout and ending up with just nine seats, compared to 47 previously. Ivana Kottasová, CNN, 5 July 2024 In yet another sign of splintering, the night also saw huge losses for Scotland’s SNP, along with big gains for the left-wing Green Party. Andreas Wiseman, Deadline, 5 July 2024 This morning, Labour gained all six of Glasgow's seats from the SNP. NBC News, 5 July 2024 The Labour Party is projected to knock the SNP out of the majority of Scotland’s seats in the July 4 parliamentary elections, potentially reducing the SNP to just a quarter of its current total. Lenora Chu, The Christian Science Monitor, 1 July 2024

Word History

Etymology

single nucleotide polymorphism

First Known Use

1991, in the meaning defined above

Time Traveler
The first known use of SNP was in 1991

Browse Nearby Words

Cite this Entry

“SNP.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/SNP. Accessed 16 Sep. 2025.

Medical Definition

SNP

noun
: a variant DNA sequence in which the purine or pyrimidine base (as cytosine) of a single nucleotide has been replaced by another such base (as thymine)
Most SNPs occur in places in the genome that aren't used for making proteins—the so-called junk DNA. But the few SNPs that land squarely in a gene or in a regulatory region near a gene can alter characteristics influenced by that gene …Christen Brownlee, Science News
The ultimate goal of the pharmaceutical industry is to find the SNPs involved with major diseases and use them to find specific molecular targets for drugs.Tim Friend, USA Today

called also single nucleotide polymorphism

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