: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide

Examples of nicotine in a Sentence

Recent Examples on the Web
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The habits most consistently linked to lower blood pressure include eating a balanced diet with plenty of fresh vegetables and fruit, exercising regularly, managing stress, limiting alcohol and avoiding tobacco and nicotine products. — Hanna Wickes, Charlotte Observer, 25 Sep. 2026 Because high-potency vapes drive up physical tolerance, standard quitting aids — like over-the-counter patches or nicotine gum — can sometimes feel inadequate to a user seeking immediate relief. — Khloe Quill, FOXNews.com, 24 Sep. 2026 This trend includes use of nicotine alone in noncombustible products such as nicotine pouches, or in combination with caffeine and nootropics, which are substances marketed to enhance cognition. — Hasmeena Kathuria, The Conversation, 22 Sep. 2026 See All Example Sentences for nicotine

Word History

Etymology

French, from New Latin nicotiana

First Known Use

1817, in the meaning defined above

Time Traveler
The first known use of nicotine was in 1817

Cite this Entry

“Nicotine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nicotine. Accessed 28 Sep. 2026.

Kids Definition

nicotine

noun
: a poisonous substance found in tobacco and used as an insecticide

Medical Definition

nicotine

noun
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and that is used as an insecticide and is sometimes used in smoking cessation aids

Note: Trademarks for nicotine include Nicoderm, Nicorette, and Nicotrol.

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