: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide

Examples of nicotine in a Sentence

Recent Examples on the Web
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The past year has seen a growing number of influencers, many of whom are aligned with the Make America Healthy Again movement, promoting nicotine as a health product. Jamie Hartmann-Boyce, The Conversation, 17 Aug. 2026 Beyond gas, nicotine pouches, beverages, and foodservice were common callouts as sales growth drivers for the cohort, according to JPMorgan analyst Thomas Palmer. Norah Rami, Fortune, 14 Aug. 2026 The survey first began asking about nicotine pouches like Zyn in 2023. Sarah Todd, STAT, 12 Aug. 2026 Most of the products were flavored nicotine vapes, which accounted for 76% of the items seized. Carlos E. Castañeda, CBS News, 11 Aug. 2026 See All Example Sentences for nicotine

Word History

Etymology

French, from New Latin nicotiana

First Known Use

1817, in the meaning defined above

Time Traveler
The first known use of nicotine was in 1817

Cite this Entry

“Nicotine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nicotine. Accessed 19 Aug. 2026.

Kids Definition

nicotine

noun
: a poisonous substance found in tobacco and used as an insecticide

Medical Definition

nicotine

noun
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and that is used as an insecticide and is sometimes used in smoking cessation aids

Note: Trademarks for nicotine include Nicoderm, Nicorette, and Nicotrol.

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