liver

1 of 2

noun (1)

liv·​er ˈli-vər 

1

a

: a large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood (as by converting sugars into glycogen which it stores up until required and by forming urea)

b

: any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes

2

archaic : a determinant of the quality or temper of a human being

3

: the liver of an animal (such as a calf or chicken) eaten as food

4

: a grayish reddish brown

called also liver brown, liver maroon

liver

2 of 2

noun (2)

liv·​er ˈli-vər 

1

: one that lives especially in a specified way

a fast liver

2

: resident

Examples of liver in a Sentence

Recent Examples on the Web

Noun

Current phase-specific guidance points to iron-rich foods during menstruation to replace losses, lighter liver-supporting foods in the follicular phase, anti-inflammatory foods in the luteal phase and magnesium and B6 in the late luteal phase for PMS support. —Allison Palmer updated June 13, Fort Worth Star-Telegram, 13 June 2026

In another recent study examining over 10,000 patients with early stage cancer, GLP-1 drugs reduced the progression of cancer to a more advanced stage across six different tumors, including colon, breast, liver and lung cancer. —Omer Awan, Forbes.com, 13 June 2026

The test showed spots on her liver and a mass in her colon. —Kerry Breen, CBS News, 13 June 2026

Other risk factors for breast cancer in men include being over the age of 50, a family history of breast cancer, obesity, exposure to hormone and radiation therapy treatments, liver disease and certain conditions that affect the testicles, according to the CDC. —ABC News, 10 June 2026

Word History

Etymology

Noun (1)

Middle English, from Old English lifer; akin to Old High German lebra liver

First Known Use

Noun (1)

before the 12th century, in the meaning defined at sense 1a

Noun (2)

14th century, in the meaning defined at sense 1

Phrases Containing liver

• chopped liver
• cod-liver oil
• liver fluke
• liver pudding
• liver sausage
• liver spots

Rhymes for liver

• giver
• livre
• quiver
• river
• shiver
• sliver
• caregiver
• deliver
• downriver
• lawgiver
• upriver

Kids Definition

liver

1 of 2 noun

liv·​er ˈliv-ər 

1

a

: a large glandular organ of vertebrates that secretes bile and causes changes in the blood (as by changing sugars into glycogen and by forming urea)

b

: any of various large probably digestive glands of invertebrate animals

2

: the liver of an animal (as of a calf or chicken) eaten as food

liver

2 of 2 noun

liv·​er ˈliv-ər 

: one that lives especially in a specified way

Medical Definition

liver

noun

liv·​er ˈliv-ər 

1

a

: a large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood which passes through it (as by converting sugars into glycogen which it stores up until required and by forming urea), that in humans is the largest gland in the body, weighs from 40 to 60 ounces (1100 to 1700 grams), is a dark red color, and occupies the upper right portion of the abdominal cavity immediately below the diaphragm, that is divided by fissures into five lobes, and that receives blood both from the hepatic artery and the portal vein and returns it to the systemic circulation by the hepatic veins

b

: any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes

2

: the liver of an animal (as a calf or pig) eaten as food or used as a source of pharmaceutical products (as liver extract)

3

: disease or disorder of the liver : biliousness