1
a
: a large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood (as by converting sugars into glycogen which it stores up until required and by forming urea)
b
: any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes
2
archaic : a determinant of the quality or temper of a human being
3
: the liver of an animal (such as a calf or chicken) eaten as food
4
: a grayish reddish brown

called also liver brown, liver maroon

1
: one that lives especially in a specified way
a fast liver
2

Examples of liver in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Noun
Shapiro says those with dealing with health issues such gallstones or bile duct obstruction, kidney stones, iron-deficiency anemia, and liver disease should consult their doctors. Nadine El Chaer, Vogue, 19 Sep. 2026 Because insoluble fiber is not actually digested, it’s broken down and fermented by the good bacteria in your gut, which produce short-chain fatty acids that signal to your liver to stop producing as much glucose. Mira Miller, Verywell Health, 17 Sep. 2026 However, high doses (more than one-fourth teaspoon ground) could be harmful to the liver, so those with liver issues should be cautious. Sarah Garone, HEALTH, 16 Sep. 2026 While presenting, the trio took a moment to shout out their late Charlie’s Angels costar Farrah Fawcett, who died in 2009 from anal cancer that metastasized to her liver at age 62. Nicki Cox, PEOPLE, 15 Sep. 2026 See All Example Sentences for liver

Word History

Etymology

Noun (1)

Middle English, from Old English lifer; akin to Old High German lebra liver

First Known Use

Noun (1)

before the 12th century, in the meaning defined at sense 1a

Noun (2)

14th century, in the meaning defined at sense 1

Time Traveler
The first known use of liver was before the 12th century

Cite this Entry

“Liver.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/liver. Accessed 23 Sep. 2026.

Kids Definition

liver

1 of 2 noun
1
a
: a large glandular organ of vertebrates that secretes bile and causes changes in the blood (as by changing sugars into glycogen and by forming urea)
b
: any of various large probably digestive glands of invertebrate animals
2
: the liver of an animal (as of a calf or chicken) eaten as food

liver

2 of 2 noun
: one that lives especially in a specified way

Medical Definition

1
a
: a large very vascular glandular organ of vertebrates that secretes bile and causes important changes in many of the substances contained in the blood which passes through it (as by converting sugars into glycogen which it stores up until required and by forming urea), that in humans is the largest gland in the body, weighs from 40 to 60 ounces (1100 to 1700 grams), is a dark red color, and occupies the upper right portion of the abdominal cavity immediately below the diaphragm, that is divided by fissures into five lobes, and that receives blood both from the hepatic artery and the portal vein and returns it to the systemic circulation by the hepatic veins
b
: any of various large compound glands associated with the digestive tract of invertebrate animals and probably concerned with the secretion of digestive enzymes
2
: the liver of an animal (as a calf or pig) eaten as food or used as a source of pharmaceutical products (as liver extract)
3
: disease or disorder of the liver : biliousness

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