insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

Becoming more active contributes to improved insulin resistance, which protects against diabetes risk and helps manage diabetes symptoms. —Laura Baehr, The Conversation, 7 May 2026

Patients may have higher rates of metabolic conditions (like insulin resistance or obesity), cardiovascular risk factors and also other inflammatory diseases like psoriasis or arthritis. —Lauryn Higgins, Flow Space, 6 May 2026

This is particularly important for those with insulin resistance or type 2 diabetes. —Daryl Austin, USA Today, 3 May 2026

The Risk Factors Worth Tracking at Midlife There is no cure for type 2 diabetes, and Mayo Clinic identifies insulin resistance as the main cause. —Samantha Agate, Sacbee.com, 1 May 2026

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes