insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

In the premium version of the app, Health Guardian also monitors blood pressure, insulin resistance, and sleeping trends. — Andrew Gebhart, PC Magazine, 12 Oct. 2026

Visceral fat, which sits deep inside the abdomen wrapped around internal organs, affects metabolism and influences insulin resistance. — Sadie Chafe, FOXNews.com, 11 Oct. 2026

It is often associated with insulin resistance, obesity, or certain endocrine disorders. — Glamour, 2 Oct. 2026

Damman noted that even five minutes of getting the heart rate up after a meal is enough to blunt the post-meal spike, which points to real potential for people managing insulin resistance or a family history of type 2 diabetes. — Hanna Wickes, Fort Worth Star-Telegram, 24 Sep. 2026

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes