insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (such as glucose uptake and lipolysis) that is typical of type 2 diabetes but often occurs in the absence of diabetes

Examples of insulin resistance in a Sentence

Recent Examples on the Web

Many of those are tied to inflammation and insulin resistance. — ABC News, 29 Oct. 2026

Both foods are sources of vitamin E, an antioxidant linked to improvements in long-term blood sugar levels and insulin resistance in people with diabetes. — Brittany Lubeck, Verywell Health, 28 Oct. 2026

Pomegranates Pomegranate intake may lower blood pressure, blood sugar, and cholesterol levels, and improve insulin resistance. — Jillian Kubala, HEALTH, 23 Oct. 2026

In the premium version of the app, Health Guardian also monitors blood pressure, insulin resistance, and sleeping trends. — Andrew Gebhart, PC Magazine, 12 Oct. 2026

Word History

First Known Use

1927, in the meaning defined above

Rhymes for insulin resistance

• magnetoresistance
• assistance
• consistence
• desistance
• existence
• insistence
• persistence
• subsistence
• coexistence
• nonexistence
• distance

Medical Definition

insulin resistance

noun

: reduced sensitivity to insulin by the body's insulin-dependent processes (as glucose uptake, lipolysis, and inhibition of glucose production by the liver) that results in decreased activity of these processes or an increase in insulin production or both and that is typical of type 2 diabetes but often occurs in the absence of diabetes