1
: the major histocompatibility complex in humans
2
: a genetic locus, gene, or antigen of HLA
often used with one or more letters to designate a locus or with letters and a number to designate an allele at the locus or the antigen corresponding to the locus and allele

Word History

Etymology

human leukocyte antigen

First Known Use

1968, in the meaning defined at sense 1

Time Traveler
The first known use of HLA was in 1968

Dictionary Entries Near HLA

Cite this Entry

“HLA.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/HLA. Accessed 2 Feb. 2023.

Medical Definition

HLA

noun
variants also HL-A
1
: the major histocompatibility complex in humans
2
: a genetic locus, gene, or antigen of the major histocompatibility complex in humans
often used attributively
HLA antigensHLA typing
often used with one or more letters to designate a locus or with letters and a number to designate an allele at the locus or the antigen corresponding to the locus and allele
relationship … between HLA-B27 antigen and ankylosing spondylitisG. E. Ehrlich

History and Etymology for HLA

human leukocyte antigen

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