: any of a breed of tall massive powerful smooth-coated dogs
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Spreading joy with Wally, his boxer, Great Dane, hound mix, or his grand-dog, Aja — who are both certified therapy dogs — Derene visits schools, active living communities and other locations.—Lesly Gregory, AJC.com, 18 Mar. 2026 In spite of the frigid weather, pavilions hosting the more popular breeds—the pug, the Doberman pinscher, the Great Dane, the St. Bernard—were packed.—John Seabrook, New Yorker, 16 Mar. 2026 The Great Dane puppy at the center of the mystery is, of course, Scooby-Doo himself.—Hanna Wickes, Charlotte Observer, 24 Feb. 2026 Owen Wilson Has Always Been A Dog Lover Having starred in the heartfelt 2008 canine classic Marley & Me, as well as voicing the title character of the Great Dane in the 2010 live-action animal adventure Marmaduke, Owen Wilson is certainly no stranger to being a central character in dog movies.—Tim Lammers, Forbes.com, 16 Jan. 2026 See All Example Sentences for Great Dane