G protein

noun

variants or G-protein
ˈjē-ˈprō-ˌtēn How to pronounce G protein (audio)
-ˈprō-tē-ən
plural G proteins or G-proteins
: any of a class of cell membrane proteins that are coupled to cell surface receptors and upon stimulation of the receptor by an extracellular signaling molecule (such as a hormone or neurotransmitter) bind to GTP to form an active complex which mediates an intracellular event (such as activation of adenylate cyclase)

Word History

Etymology

guanosine triphosphate-binding protein

First Known Use

1975, in the meaning defined above

Time Traveler
The first known use of G protein was in 1975

Dictionary Entries Near G protein

Cite this Entry

“G protein.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/G%20protein. Accessed 23 Apr. 2024.

Medical Definition

G protein

noun
variants or G-protein
: any of a class of cell membrane proteins that are coupled to cell surface receptors and upon stimulation of the receptor by an extracellular molecule (as a hormone or neurotransmitter) bind to GTP to form an active complex which mediates an intracellular event (as activation of adenylate cyclase)
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!