: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally (as by intravenous or epidural injection)

Examples of fentanyl in a Sentence

Recent Examples on the Web
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The evidence also proved that the fentanyl Walker delivered caused the victim’s fatal overdose, prosecutors said. Ceci Urbanski, Chicago Tribune, 17 July 2026 Gregg provided narcotics, including fentanyl, to 31-year-old Alexandrea Hunter, resulting in the woman’s death on Christmas Eve in 2023, according to court documents. Caroline Zimmerman, Kansas City Star, 15 July 2026 Now the market is mostly powdered fentanyl, and drug deaths are rising. Josh Katz, New York Times, 15 July 2026 Jimmy, an 18-month-old German shepherd-Belgian Malinois mix from Europe, is certified in apprehension and the detection of methamphetamine, cocaine, heroin and fentanyl. Nicole Buss, Sacbee.com, 14 July 2026 See All Example Sentences for fentanyl

Word History

Etymology

probably alteration of phenethyl, a monovalent radical derived from ethylbenzine, from phen- + ethyl

First Known Use

1964, in the meaning defined above

Time Traveler
The first known use of fentanyl was in 1964

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Cite this Entry

“Fentanyl.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/fentanyl. Accessed 21 Jul. 2026.

Medical Definition

: a synthetic opioid narcotic analgesic C22H28N2O with pharmacological action similar to morphine that is administered transdermally as a skin patch and in the form of its citrate C22H28N2O·C6H8O7 is administered orally or parenterally

Note: Fentanyl is marketed under the trademark Actiq.

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