plural E. coli
: an enterobacterium (Escherichia coli) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness see enterobacterium illustration

Examples of E. coli in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
The collapse led to a spike in E. coli in the surrounding area, which DC Water initially underestimated by a sweeping margin. Emily Hallas, The Washington Examiner, 21 Feb. 2026 Responders should wear personal protective equipment during those calls due to the dangerous levels of E. coli and other contaminants in the water. Isabelle Schmeler, NBC news, 18 Feb. 2026 The spill has prompted widespread public health concerns as E. coli bacteria have been detected at dangerous levels in parts of the river, and the leakage underscores the risks posed by aging sewer infrastructure. Kathryn Palmer, USA Today, 18 Feb. 2026 Government and independent researchers have monitored the quality of the water at and downstream from the rupture, testing for E. coli bacteria. Ryan Mancini, The Hill, 17 Feb. 2026 See All Example Sentences for E. coli

Word History

First Known Use

1925, in the meaning defined above

Time Traveler
The first known use of E. coli was in 1925

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Cite this Entry

“E. coli.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/E.%20coli. Accessed 1 Mar. 2026.

Kids Definition

E. coli

noun
plural E. coli
: a bacterium in the shape of a short rod that may cause intestinal illness
Etymology

short for Escherichia coli, the taxonomic name in biology

Medical Definition

E. coli

noun
ˌē-ˈkō-ˌlī
plural E. coli also E. colis
: a straight rod-shaped gram-negative bacterium (Escherichia coli of the family Enterobacteriaceae) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness marked especially by diarrhea
one million acid-resistant E. coli per gram of fecesJohn Schwartz
this E. coli can survive … longer than all the other E. colisEd Geldreich
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