plural E. coli
: an enterobacterium (Escherichia coli) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness see enterobacterium illustration

Examples of E. coli in a Sentence

Recent Examples on the Web
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And a 2023 study found foodborne E. coli was likely behind more than 480,000 urinary tract infections in the U.S. each year. Miriam Fauzia, Dallas Morning News, 29 Jan. 2026 The technology demonstrated bacterial reduction during operation, including coliforms and E. coli. Walker Armstrong, San Diego Union-Tribune, 25 Jan. 2026 That's according to a study by the Center for Food as Medicine and Longevity, which reviewed data from 10 major airlines and 11 regional airlines over a three year period, examining aircraft violations, violations for E. coli, disinfecting and flushing frequency, and more. Evie Carrick, Travel + Leisure, 22 Jan. 2026 Even with the challenges — sleeping in hostels for a few dollars a night, dealing with bugs, getting food poisoning and even a bout of E. coli that landed him in the hospital — Sklavos says the experience has been worth it. Jordan Greene, PEOPLE, 22 Jan. 2026 See All Example Sentences for E. coli

Word History

First Known Use

1925, in the meaning defined above

Time Traveler
The first known use of E. coli was in 1925

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Cite this Entry

“E. coli.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/E.%20coli. Accessed 8 Feb. 2026.

Kids Definition

E. coli

noun
plural E. coli
: a bacterium in the shape of a short rod that may cause intestinal illness
Etymology

short for Escherichia coli, the taxonomic name in biology

Medical Definition

E. coli

noun
ˌē-ˈkō-ˌlī
plural E. coli also E. colis
: a straight rod-shaped gram-negative bacterium (Escherichia coli of the family Enterobacteriaceae) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness marked especially by diarrhea
one million acid-resistant E. coli per gram of fecesJohn Schwartz
this E. coli can survive … longer than all the other E. colisEd Geldreich
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