plural E. coli
: an enterobacterium (Escherichia coli) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness see enterobacterium illustration

Examples of E. coli in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Water samples are tested for E. coli to determine the need for beach closures. Elyssa Kaufman, CBS News, 23 June 2026 One such novel hypothesis that Mythos came up with—identifying a specific protein in E. coli bacteria as a target for new antimicrobial therapies—has in fact already been validated in physical laboratory testing. Rob Toews, Forbes.com, 22 June 2026 The Iowa Department of Natural Resources (DNR) warned people that swimming is not recommended at Backbone Beach, Pine Lake South Beach, Geode Lake Beach, Union Grove Beach, Pleasant Creek Beach and Nine Eagles Beach due to elevated E. coli levels. Teresa Mull, FOXNews.com, 20 June 2026 Over in Iowa, the state's Department of Natural Resources has listed at least five beaches across the state as unfit for swimming due to the presence of E. coli, including Black Hawk Beach in Lake View, Pleasant Creek in Palo, Backbone in Dundee and Lake Darling in Brighton. Christopher Edwards, PEOPLE, 19 June 2026 See All Example Sentences for E. coli

Word History

First Known Use

1925, in the meaning defined above

Time Traveler
The first known use of E. coli was in 1925

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Cite this Entry

“E. coli.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/E.%20coli. Accessed 28 Jun. 2026.

Kids Definition

E. coli

noun
plural E. coli
: a bacterium in the shape of a short rod that may cause intestinal illness
Etymology

short for Escherichia coli, the taxonomic name in biology

Medical Definition

E. coli

noun
ˌē-ˈkō-ˌlī
plural E. coli also E. colis
: a straight rod-shaped gram-negative bacterium (Escherichia coli of the family Enterobacteriaceae) that is used in public health as an indicator of fecal pollution (as of water or food) and in medicine and genetics as a research organism and that occurs in various strains that may live as harmless inhabitants of the human lower intestine or may produce a toxin causing intestinal illness marked especially by diarrhea
one million acid-resistant E. coli per gram of fecesJohn Schwartz
this E. coli can survive … longer than all the other E. colisEd Geldreich
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