Definition of Creutzfeldt–Jakob disease
: a rare progressive fatal encephalopathy caused by a prion and marked by development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination
Origin and Etymology of creutzfeldt–jakob disease
Hans G. Creutzfeldt †1964 German psychiatrist and Alfons M. Jakob †1931 German psychiatrist
First Known Use: 1963See Words from the same year
CREUTZFELDT–JAKOB DISEASE Defined for English Language Learners
Definition of Creutzfeldt–Jakob disease for English Language Learners
medical : a disease of the brain that causes people to lose their memory, to no longer be able to control their muscles, and eventually to die
Medical Definition of Creutzfeldt–Jakob disease
: a rare progressive fatal prion disease marked by the development of porous brain tissue, premature dementia in middle age, and gradual loss of muscular coordination—abbreviation CJD; called also Jakob-Creutzfeldt disease; see variant creutzfeldt-jakob disease
Biographical Note for creutzfeldt–jakob disease
Hans Gerhard (1885–1964), and
Alfons Maria (1884–1931), German psychiatrists. Creutzfeldt published his description of the disease now known as Creutzfeldt-Jakob disease in 1920. A year later in the same neurological journal Jakob offered his description. Although Creutzfeldt's description is the original one, Jakob's is the better known of the two, so the disease is named in honor of both men.
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