cirrhosis

noun

cir·​rho·​sis sə-ˈrō-səs How to pronounce cirrhosis (audio)
plural cirrhoses sə-ˈrō-ˌsēz How to pronounce cirrhosis (audio)
: widespread disruption of normal liver structure by fibrosis and the formation of regenerative nodules that is caused by any of various chronic progressive conditions affecting the liver (such as long-term alcohol abuse or hepatitis)
cirrhotic adjective or noun

Examples of cirrhosis in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Steelman died of cirrhosis of the liver in 1986 — the same year that Greenberg, a scrappy reporter for City magazine in Tucson, got a tip about Gretzler that sparked her curiosity. Stephanie Nolasco, FOXNews.com, 11 Jan. 2026 The study found that in cirrhosis, a change in gene regulation, specifically the removal of chemical marks from the PAF-R gene, causes the gene to become overactive. Pranjal Malewar, New Atlas, 11 Jan. 2026 The disease causes liver cancer, cirrhosis, and other serious illnesses and is particularly dangerous when contracted by babies and young children. Arthur Allen, NPR, 9 Jan. 2026 Documents obtained by the outlet show that Sean died from an acute upper gastrointestinal bleed and severe metabolic acidosis, complications brought on by alcoholic liver cirrhosis. Vivian Kwarm, New York Daily News, 8 Jan. 2026 See All Example Sentences for cirrhosis

Word History

Etymology

New Latin, from Greek kirrhos orange-colored; akin to Old English hār gray — more at hoar

First Known Use

circa 1847, in the meaning defined above

Time Traveler
The first known use of cirrhosis was circa 1847

Browse Nearby Words

Cite this Entry

“Cirrhosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cirrhosis. Accessed 19 Jan. 2026.

Kids Definition

cirrhosis

noun
cir·​rho·​sis sə-ˈrō-səs How to pronounce cirrhosis (audio)
: an increase in fiber-containing tissue and hardening of the liver

Medical Definition

cirrhosis

noun
cir·​rho·​sis sə-ˈrō-səs How to pronounce cirrhosis (audio)
plural cirrhoses -ˌsēz How to pronounce cirrhosis (audio)
: widespread disruption of normal liver structure by fibrosis and the formation of regenerative nodules that is caused by any of various chronic progressive conditions affecting the liver (as long-term alcohol abuse or hepatitis) see biliary cirrhosis

More from Merriam-Webster on cirrhosis

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