: widespread disruption of normal liver structure by fibrosis and the formation of regenerative nodules that is caused by any of various chronic progressive conditions affecting the liver (such as long-term alcohol abuse or hepatitis)

Examples of cirrhosis in a Sentence

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Other contributing factors included hypertensive cardiovascular disease and cirrhosis due to alcoholism. Sofi Zeman august 25, Kansas City Star, 26 Aug. 2026 Many insurers also still require proof of sobriety or documented cirrhosis before covering direct-acting antivirals. William A. Haseltine, Forbes.com, 21 Aug. 2026 Studies also show that tomatoes can help reduce the risk of fatty liver disease, which can lead to cirrhosis, scarring of the liver, or even liver cancer. Audrey Noble, Vogue, 24 July 2026 The liver-transplant reports renewed speculation about addiction because the most common reason people suffer serious liver dysfunction and need a new liver is cirrhosis, according to the American Liver Foundation. Martha Ross, Mercury News, 17 July 2026 See All Example Sentences for cirrhosis

Word History

Etymology

New Latin, from Greek kirrhos orange-colored; akin to Old English hār gray — more at hoar

First Known Use

circa 1847, in the meaning defined above

Time Traveler
The first known use of cirrhosis was circa 1847

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Cite this Entry

“Cirrhosis.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/cirrhosis. Accessed 1 Sep. 2026.

Kids Definition

cirrhosis

noun
: an increase in fiber-containing tissue and hardening of the liver

Medical Definition

cirrhosis

noun
: widespread disruption of normal liver structure by fibrosis and the formation of regenerative nodules that is caused by any of various chronic progressive conditions affecting the liver (as long-term alcohol abuse or hepatitis) see biliary cirrhosis

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