COX-2 inhibitor

\ ˈkäks-ˈtü- How to pronounce COX-2 inhibitor (audio) \

Definition of COX-2 inhibitor

: any of a class of drugs used to treat the pain and inflammation of arthritis by selectively blocking the variant of cyclooxygenase causing these symptoms

First Known Use of COX-2 inhibitor

1994, in the meaning defined above

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The first known use of COX-2 inhibitor was in 1994

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Cite this Entry

“COX-2 inhibitor.” Dictionary, Merriam-Webster, Accessed 14 Apr. 2021.

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More Definitions for COX-2 inhibitor

COX-2 inhibitor

variants: also COX-2 blocker

Medical Definition of COX-2 inhibitor

: any of a class of drugs (as celecoxib) that are NSAIDs which selectively block the isoform COX-2 but not the isoform COX-1 of cyclooxygenase and are used chiefly to relieve the pain and inflammation of arthritis while minimizing gastrointestinal side effects COX-2 inhibitors, as their name implies, were designed to block just the inflammatory functions of the COX-2 enzyme, leaving the stomach-protecting functions of the COX-1 form intact.— Alice Park, Time, 28 Feb. 2005

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