CD4

noun

\ ˌsē-(ˌ)dē-ˈfȯr

Definition of CD4

: a large glycoprotein that is found associated with a T cell receptor especially on the surface of helper T cells and that binds to a major histocompatibility complex molecule on the surface of an antigen-presenting cell to facilitate antigen recognition and T cell activation — often used before another noun the CD4 geneCD4 T cells [=T cells bearing CD4 on their surface]

Note: CD4 is a receptor for HIV, and cells of the immune system bearing CD4 on their surface are preferentially infected with the virus and become progressively depleted.

— compare CD8

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“CD4.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/CD4. Accessed 16 Oct. 2021.

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CD4

noun

\ -ˈfōr, -ˈfȯr

Medical Definition of CD4

: a large glycoprotein that is found associated with a T cell receptor especially on the surface of helper T cells and that binds to a major histocompatibility complex molecule on the surface of an antigen-presenting cell to facilitate antigen recognition and T cell activation —often used before another noun the CD4 geneCD4 T cells [=T cells bearing CD4 on their surface]

Note: CD4 is a receptor for HIV and cells of the immune system bearing CD4 on their surface are preferentially infected with the virus and become progressively depleted.

— compare cd8