C-reactive protein


C-re·​ac·​tive protein ˈsē-rē-ˈak-tiv- How to pronounce C-reactive protein (audio)
: a protein present in blood serum in various abnormal states (such as inflammation or neoplasia)
abbreviation CRP

Word History


C-polysaccharide, a polysaccharide found in the cell wall of pneumococci and precipitated by this protein, from carbohydrate

First Known Use

1955, in the meaning defined above

Time Traveler
The first known use of C-reactive protein was in 1955

Dictionary Entries Near C-reactive protein

Cite this Entry

“C-reactive protein.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/C-reactive%20protein. Accessed 3 Feb. 2023.

Medical Definition

C-reactive protein

C-re·​ac·​tive protein ˌsē-rē-ˌak-tiv- How to pronounce C-reactive protein (audio)
: a protein produced by the liver that is normally present in trace amounts in the blood serum but is elevated during episodes of acute inflammation (as those associated with neoplastic disease, chronic infection, or coronary artery disease)
Love words? Need even more definitions?

Subscribe to America's largest dictionary and get thousands more definitions and advanced search—ad free!

The Great British Vocabulary Quiz

  • union jack speech bubble
  • Named after Sir Robert Peel, what are British police called?
Spell It

Hear a word and type it out. How many can you get right?

Solve today's spelling word game by finding as many words as you can with using just 7 letters. Longer words score more points.

Can you make 12 words with 7 letters?