backbone

noun

back·​bone ˈbak-ˈbōn 

-ˌbōn

1

: spinal column, spine

2

: something that resembles a backbone: such as

a

: a chief mountain ridge, range, or system

b

: the foundation or most substantial or sturdiest part of something

c

: the longest chain of atoms or groups of atoms in a usually long molecule (such as a polymer or protein)

d

: the primary high-speed hardware and transmission lines of a telecommunications network (such as the Internet)

3

: firm and resolute character

4

: spine sense 1c

backboned

ˈbak-ˌbōnd 

adjective

Synonyms of backbone

• spine

Examples of backbone in a Sentence

She is the backbone of the family.

He showed some backbone by refusing to compromise his values.

Recent Examples on the Web

While colorful berries and occasional blooms pepper the winter landscape, evergreen shrubs form the backbone of the garden, carrying it through the season. —Kim Toscano, Southern Living, 19 Dec. 2025

The technological backbone of the vaccines, known as mRNA, has been in development for decades by scientists who won the 2023 Nobel Prize in medicine. —Jessica Schreifels, CNN Money, 18 Dec. 2025

Data centers—the physical backbone of the virtual revolution—require absurd amounts (as in eight times more than the typical computing workload) of electricity to both train AI models and operate them. —Alexandra Harrell, Sourcing Journal, 18 Dec. 2025

Silicon Valley and Washington sees data centers as the backbone of America’s AI future. —Eva Roytburg, Fortune, 16 Dec. 2025

Word History

First Known Use

14th century, in the meaning defined at sense 1

Rhymes for backbone

• alone
• atone
• bemoan
• bluestone
• breastbone
• brownstone
• capstone
• cheekbone
• condone
• curbstone
• cyclone
• dethrone

Kids Definition

backbone

noun

back·​bone -ˈbōn 

-ˌbōn

1

: the skeleton of the trunk and tail of a vertebrate that consists of a jointed series of vertebrae enclosing and protecting the spinal cord

called also spinal column

2

: the foundation or sturdiest part of something

3

: firmness of character

a coward with no backbone

backboned

-ˈbōnd 

-ˌbōnd

adjective

Medical Definition

backbone

noun

back·​bone -ˈbōn, -ˌbōn 

1

: spinal column, spine

2

: the longest chain of atoms or groups of atoms in a usually long molecule (as a polymer or protein)