BRCA

noun

ˌbē-(ˌ)är-(ˌ)sē-ˈā 

ˈbra-kə

: either of two tumor suppressor genes that in mutated form tend to be associated with an increased risk of certain cancers and especially breast and ovarian cancers

—often used before another noun

BRCA genes

a BRCA mutation

Examples of BRCA in a Sentence

Recent Examples on the Web

Durand predicts that in the next decade, medical practice may move towards offering full-body imaging to more groups that are at high risk for cancer, like those with BRCA gene mutations or Lynch syndrome. —Claire Bugos, Verywell Health, 18 June 2025

Anyone identified to have the BRCA mutation based on genetic testing can begin imaging even earlier—at age 25. —Mara Santilli, Flow Space, 21 May 2025

For example, people with BRCA mutations may benefit from a poly(ADP)-ribose polymerase (PARP) inhibitor medication, which targets cancer’s ability to repair itself. —Jamin Brahmbhatt, Verywell Health, 28 Apr. 2025

The line of cozy loungers and hoodies features logos from top colleges and sports leagues—including the NBA and WNBA, with partial proceeds from those sales benefiting the Basser Center for BRCA at the University of Pennsylvania, where Martin is on the advisory board. —Joanne Fowler, People.com, 1 Apr. 2025

Word History

First Known Use

1992, in the meaning defined above

Rhymes for BRCA

• judaica
• sicca
• wicca

Medical Definition

BRCA

noun

ˌbē-(ˌ)är-(ˌ)sē-ˈā 

: either of two tumor suppressor genes that in mutated form tend to be associated with an increased risk of certain cancers and especially breast and ovarian cancers

—often used before another noun

BRCA genes

a BRCA mutation