\ ˌā-(ˌ)pē-ˈsē How to pronounce APC (audio) \

Definition of APC

 (Entry 1 of 2)

: an armored vehicle used to transport military personnel

Definition of APC (Entry 2 of 2)

antigen-presenting cell In order to trigger helper T cells, exogenous protein antigens must be taken up by antigen-presenting cells (APC) and processed into peptides that bind to MHC class II molecules.— Paola Panina-Bordignon et al.

First Known Use of APC


1952, in the meaning defined above

History and Etymology for APC


armored personnel carrier

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Cite this Entry

“APC.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/APC. Accessed 14 Aug. 2020.

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\ ˌā-ˌpē-ˈsē How to pronounce APC (audio) \

Medical Definition of APC

 (Entry 1 of 2)

: a tumor suppressor gene that in a defective form tends to be associated with a high risk of colorectal cancer Germ-line APC mutations give rise to familial adenomatous polyposis, an inherited cancer-predisposition syndrome in which more than 100 adenomatous polyps can develop; in carriers of the mutant gene, the risk of colorectal cancer by the age of 40 years is almost 100%.— Sanford D. Markowitz and Monica M. Bertagnolli, The New England Journal of Medicine, 17 Dec. 2009

Medical Definition of APC (Entry 2 of 2)

1 antigen-presenting cell When a T cell binds to such an APC, the T cell multiplies and launches an attack on cells that display the telltale protein-MHC complex—cells infected by a virus, foreign skin cells, or whatever.— Sarah Richardson, Discover, April 1996
2 aspirin, phenacetin, and caffeine The now-banned ingredient phenacetin, once widely used in APC (aspirin-phenacetin-caffeine) tablets, was found to contribute heavily to kidney disease.— Melva Weber, Vogue, March 1985

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