Synonyms of breakthrough

breakthrough

noun

ˈbrāk-ˌthrü 

as in improvement

an instance of notable progress in the development of knowledge, technology, or skill

Alexander Fleming's discovery of penicillin was one of medicine's great breakthroughs, for penicillin became the first antibiotic to successfully combat bacterial infections in humans

Synonyms & Similar Words

• improvement
• advance
• advancement
• enhancement
• development
• innovation
• discovery
• refinement
• evolution
• increase
• upturn
• upswing
• revival
• amelioration
• strengthening
• maturation
• enlightenment
• growth
• betterment
• find
• renaissance
• education
• boost
• expansion
• quantum leap
• uplift
• windfall
• gestation
• ripening
• elaboration
• civilization
• melioration
• upgrade
• perfection
• heightening
• edification
• uptrend
• renascence
• invention

Antonyms & Near Antonyms

• setback
• breakdown
• collapse
• crash
• reduction
• impediment
• hindrance
• decrease
• failing
• decline
• deterioration
• stumbling block
• worsening
• lapse
• weakening
• decay
• degeneration
• sinking
• impairment
• descent
• drawback
• shortcoming
• slowing
• lessening
• decadence
• downgrade
• detriment
• glitch
• declension
• diminishment
• disablement
• flagging
• languishment
• ebbing

Example Sentences

Recent Examples of breakthrough

In 2023, neurologists at the Feinstein Institutes for Medical Research in New York achieved a medical breakthrough that many experts believed was once impossible. — Andrew Paul, Popular Science, 16 July 2026

The breakthrough is currently confined to precision laboratory settings. — Mrigakshi Dixit, Interesting Engineering, 16 July 2026

Innovation is often measured by scientific breakthroughs, transformative technologies or pioneering discoveries. — Pradeep Khosla, San Diego Union-Tribune, 16 July 2026

Another round of final-status negotiations between Israelis and Palestinians is very unlikely to produce a breakthrough. — Thomas Wright, The Atlantic, 16 July 2026