Medical Dictionary

neurofibrillary tangle


neurofibrillary tangle

noun

Definition of NEUROFIBRILLARY TANGLE

:  a pathological accumulation of paired helical filaments composed of abnormally formed tau protein that is found chiefly in the cytoplasm of nerve cells of the brain and especially the cerebral cortex and hippocampus and that occurs typically in Alzheimer's disease
March 01, 2015
macaroni Hear it
Tube-shaped pasta or a fop or dandy
Take a 3-minute break and test your skills!
How to use a word that (literally) drives some people nuts.
Test your vocab with our fun, fast game
Ailurophobia, and 9 other unusual fears