adjective sig·nif·i·cant \sig-ˈni-fi-kənt\

: large enough to be noticed or have an effect

: very important

: having a special or hidden meaning

Full Definition of SIGNIFICANT

:  having meaning; especially :  suggestive <a significant glance>
a :  having or likely to have influence or effect :  important <a significant piece of legislation>; also :  of a noticeably or measurably large amount <a significant number of layoffs> <producing significant profits>
b :  probably caused by something other than mere chance <statistically significant correlation between vitamin deficiency and disease>


  1. A significant number of customers complained about the service.
  2. He won a significant amount of money.
  3. There is a significant difference in prices between the two stores.
  4. The study found a statistically significant decrease in symptoms in patients who had taken the drug.
  5. a significant event in the history of our nation
  6. Fish is a significant part of their diet.
  7. It is significant that she never mentioned him.
  8. He gave us a significant wink.
  9. Historians of ancient gender have seen this as crucially significant. Women in antiquity were by definition so disempowered that the authority of a new female ruler could only be captured by representing her in the guise of a man. Or so the argument goes. —Mary Beard, New York Review of Books, 12 Feb. 2009


Latin significant-, significans, present participle of significare to signify
First Known Use: 1579


adjective sig·nif·i·cant \sig-ˈnif-i-kənt\   (Medical Dictionary)

Medical Definition of SIGNIFICANT

:  probably caused by something other than mere chance <a statistically significant correlation between diet and disease>
sig·nif·i·cant·ly adverb


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