side effect

noun

: a secondary and usually adverse effect (as of a drug)
toxic side effects

called also side reaction

Examples of side effect in a Sentence

Nausea and diarrhea are the side effects of the drug. the harmful side effects of using chemicals to kill insects The merger created positive side effects for both companies.
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Early results suggest the approach helps the heart repair itself while avoiding the systemic side effects that plagued earlier drug delivery methods. Aamir Khollam, Interesting Engineering, 14 Nov. 2025 Use of either kind of these vapes can come with side effects, including drowsiness or dry mouths. Surina Venkat, The Hill, 14 Nov. 2025 Still, side effects remain a key reason why some people decide to stop taking them. Asuka Koda, CNN Money, 14 Nov. 2025 Some people may have negative digestive side effects, though. Joy Emeh, Health, 14 Nov. 2025 See All Example Sentences for side effect

Word History

First Known Use

1814, in the meaning defined above

Time Traveler
The first known use of side effect was in 1814

Browse Nearby Words

Cite this Entry

“Side effect.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/side%20effect. Accessed 18 Nov. 2025.

Kids Definition

side effect

noun
: an often harmful and unwanted effect (as of a drug) that occurs along with the basic desired effect
the environmental side effects of using chemicals to kill pests

Medical Definition

side effect

noun
: a secondary and usually adverse effect (as of a drug)
toxic side effects
a side effect of drowsiness caused by antihistamines

called also side reaction

Last Updated: - Updated example sentences
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