proteome

noun

pro·​te·​ome ˈprō-tē-ˌōm How to pronounce proteome (audio)
: the complement of proteins expressed in a cell, tissue, or organism by a genome

Examples of proteome in a Sentence

Recent Examples on the Web For example, the proteome of saliva — an exhaustive catalog of the proteins present in this fluid — is already available, and it is known that between 20 percent and 30 percent of the saliva proteome overlaps with that of blood. Matías A. Loewy, Discover Magazine, 25 Mar. 2023 For example, the proteome of saliva—an exhaustive catalog of the proteins present in this fluid—is already available, and it is known that between 20 percent and 30 percent of the saliva proteome overlaps with that of blood. Smithsonian Magazine, 17 Mar. 2023 Those transcripts are used to make the proteins in our body, naturally known as the proteome. Elizabeth Preston, Discover Magazine, 30 Mar. 2011 For a week, astronauts will use onboard microscopes to monitor how the muscle cells grow, and Huang’s team will compare the population of mRNA and proteins—the transcriptome and proteome—to corresponding samples on Earth and clinical sarcopenic tissue. Max G. Levy, Wired, 9 Aug. 2021 To construct a 'proteome', the team had to isolate venom from the jelly tentacles. Christie Wilcox, Discover Magazine, 2 June 2015 Their algorithm gobbled up the entire human proteome and spat out a preliminary list of about 43,000 peptides. Max G. Levy, Wired, 30 Nov. 2021 Nautilus is developing a protein analysis platform with the goal to identify more than 95% of the proteome. John Cumbers, Forbes, 16 June 2021 Across the board, AlphaFold2 predicted 58% of amino acids in the human proteome — all the proteins expressed by the human body — with confidence, and 35.7% with a very high degree of confidence. Katie Palmer, STAT, 22 July 2021

These examples are programmatically compiled from various online sources to illustrate current usage of the word 'proteome.' Any opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback about these examples.

Word History

Etymology

prote(in) + -ome (in genome)

Note: The term was first used in print in Valerie C. Wasinger, et al., "Progress with gene-product mapping of the Mollicutes: Mycoplasma genitalium," Electrophoresis, vol. 16, no. 7 (July, 1995), pp. 1090-94. According to Wikipedia (as of 6/30/21), proteome was coined by the Australian geneticist Marc R. Wilkins; see Marc R. Wilkins, et al., "Progress with Proteome Projects: Why All Proteins Expressed by a Genome Should be Identified and How To Do It," Biotechnology and Genetic Engineering Reviews, vol. 13 (1996), pp. 19-50; and Marc R. Wilkins, et al., "From Proteins to Proteomes: Large Scale Protein Identification by Two-Dimensional Electrophoresis and Amino Acid Analysis," Nature Biotechnology, vol. 14, issue 1 (January, 1996), pp. 61-65.

First Known Use

1995, in the meaning defined above

Time Traveler
The first known use of proteome was in 1995

Dictionary Entries Near proteome

Cite this Entry

“Proteome.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/proteome. Accessed 28 Mar. 2024.

Medical Definition

proteome

noun
pro·​te·​ome ˈprōt-ē-ˌōm How to pronounce proteome (audio)
: the complement of proteins expressed in a cell, tissue, or organism by a genome
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