genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

Esteller and the research team took samples from Branyas’ blood, saliva, urine and stool before examining her genome and comparing it with those belonging to 75 other Iberian women. —Issy Ronald, CNN Money, 26 Sep. 2025

This scenario is supported by genetic evidence found in the genomes of people alive today. —The Editors, JSTOR Daily, 25 Sep. 2025

The discovery helps explain a long-standing genetic mystery and highlights the surprising role of repetitive DNA in shaping genomes. —Neetika Walter, Interesting Engineering, 24 Sep. 2025

The defense had sought to have the key evidence excluded since it was involved the use of whole genome sequencing, a technique not previously admitted in a criminal trial in New York. —Aaron Katersky, ABC News, 23 Sep. 2025

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover