genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

In November 2020, Seibt falsely claimed that COVID-19 had not been isolated and that PCR tests were unreliable, alleging they were based solely on a computer model of the virus’s genome. —Billal Rahman, MSNBC Newsweek, 31 Oct. 2025

About 60% of our centenarians have something on their genome that interferes with the action of growth hormone. —Dominique Mosbergen, Time, 31 Oct. 2025

The brain is made up of a mosaic of cells that each have their own genome. —Jen Christensen, CNN Money, 30 Oct. 2025

Already, scientists are able to go into the genome itself to alter disease-carrying genes. —Abby McCloskey, Twin Cities, 29 Oct. 2025

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover