muscarine

noun

mus·​ca·​rine ˈmə-skə-ˌrēn How to pronounce muscarine (audio)
: a toxic alkaloid base [C9H20NO2]+ that is biochemically related to acetylcholine, is found especially in fly agaric, and acts directly on smooth muscle

Word History

Etymology

German Muskarin, from New Latin (Amanita) muscaria fly agaric

First Known Use

1872, in the meaning defined above

Time Traveler
The first known use of muscarine was in 1872

Browse Nearby Words

Cite this Entry

“Muscarine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/muscarine. Accessed 3 Jul. 2026.

Medical Definition

muscarine

noun
mus·​ca·​rine ˈməs-kə-ˌrēn How to pronounce muscarine (audio)
: a toxic ammonium base [C9H20NO2]+ that is biochemically related to acetylcholine, was originally extracted from fly agaric but also occurs in other mushrooms (as of the genus Inocybe), and when ingested produces symptoms of parasympathetic nervous system stimulation (as excessive salivation, lacrimation, bronchial secretion, diarrhea, miosis, and bradycardia)

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