Some analysts are issuing dire economic forecasts.
They live in dire poverty.
The alleged threat posed by Yellowstone's 3,600 buffalo came from the fact that they carry brucella, a bacterium that cycles harmlessly enough in Bison bison but has considerably more dire effects on cattle. —Christopher Ketcham, Harper's , June 2008
Whether one is a lowly farmer or an urban worker, a student, professional, or a member of the elite, a meal is not complete unless rice is served to accompany the main viand of pork, fish, chicken, beef, vegetables or in the most dire circumstances, dry fish or salt. —Georgina R. Encanto, Food , April 2000
All wild tigers are threatened with extinction, but Sumatran tigers are in especially dire straits because the world's zoos have only 235 of them in captive-breeding programs. —Audubon, November-December 1998