Synonyms of irritation

irritation

noun

ˌir-ə-ˈtā-shən 

as in frustration

the feeling of impatience or anger caused by another's repeated disagreeable acts

Dad's general irritation at the incessant complaining coming from the back seat of the car

Synonyms & Similar Words

• frustration
• exasperation
• annoyance
• displeasure
• grief
• discomfort
• anger
• aggravation
• vexation
• indignation
• irritability
• bother
• trouble
• agitation
• distress
• pip
• upset
• outrage
• resentment
• botheration
• disturbance
• aggro
• perturbation
• pique
• irritableness
• pet
• ire
• umbrage
• angriness
• dander
• dudgeon
• snappishness
• gall
• peeve
• huff
• chafe
• irateness

Antonyms & Near Antonyms

• pleasure
• delight

Example Sentences

Recent Examples of irritation

And on top of worrying about the start of school, Silva said her family is still suffering from headaches, nausea, sore throats, eye irritation, stomach pain, diarrhea and persistent coughing. — Howard Blume, Los Angeles Times, 30 July 2026

That stronger is better, or that peeling and irritation mean that retinol is working. — Rachel Burchfield, Forbes.com, 29 July 2026

Trapped moisture, particularly in the ears and skin folds, can allow yeast and bacteria to grow, potentially leading to irritation or infection. — Lauren Paige Richeson, USA Today, 29 July 2026

The gel is widely recognized for its soothing effects on the skin, especially for minor burns and irritation. — Morgan Pearson, Verywell Health, 29 July 2026