Medical Definition of sign
1: one of a set of gestures used to represent language
2: an objective evidence of disease especially as observed and interpreted by the physician rather than by the patient or lay observer <narrow retinal vessels are a sign of arteriosclerosis>—see brudzinski sign, chvostek's sign, homans' sign, kernig sign, physical sign, placental sign, romberg's sign, tinel's sign, vital signs, von graefe's sign; compare symptom
Learn More about sign
Seen and Heard
What made you want to look up sign? Please tell us where you read or heard it (including the quote, if possible).