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Medical Dictionary


adj re·frac·to·ry \ri-ˈfrak-t(ə-)rē\

Medical Definition of REFRACTORY

:  resistant to treatment or cure <a refractory fulminant lesion> <had disease that was extremely refractory to multiple intensive therapies—Michelle L. Bennett et al>
:  unresponsive to stimulus <the refractory period of a muscle fiber>
:  resistant or not responding to an infectious agent :  immune <refractory to reinfection>
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