Medical Dictionary

pernicious anemia


Medical Definition of PERNICIOUS ANEMIA

:  a severe hyperchromic anemia marked by a progressive decrease in number and increase in size and hemoglobin content of the red blood cells and by pallor, weakness, and gastrointestinal and nervous disturbances and associated with reduced ability to absorb vitamin B12 due to the absence of intrinsic factor—called also addisonian anemia


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