pernicious anemia

pernicious anemia

noun

Definition of PERNICIOUS ANEMIA

: a severe hyperchromic anemia marked by a progressive decrease in number and increase in size and hemoglobin content of the red blood cells and by pallor, weakness, and gastrointestinal and nervous disturbances and associated with reduced ability to absorb vitamin B₁₂ due to the absence of intrinsic factor—called also addisonian anemia