Marfan+syndrome

One entry found for Marfan syndrome.

Main Entry: Mar·fan syndrome
Pronunciation: mär-fan-
Variant(s): or Mar·fan's syndrome /-fanz-/
Function: noun
: a disorder of connective tissue that is inherited as a simple dominant trait, is caused by a defect in the gene controlling the production of fibrillin, and is characterized by abnormal elongation of the long bones and often by ocular and circulatory defects
Mar·fan /mr-fäⁿ/ , Antonin Bernard Jean (1858-1942), French pediatrician. Marfan concerned himself with the prevention, diagnosis, and treatment of children's diseases. In 1892 he described spastic paralysis in children with hereditary syphilis. In 1896 he described a syndrome marked by arachnodactyly, ectopia of the crystalline lens, and abnormal flexibility of the joints. The syndrome now bears his name.