Main Entry: Bence–Jones protein

Pronunciation: \ˌben(t)s-ˌjōnz-\

Function: noun

: a polypeptide composed of one or two antibody light chains that is found especially in the urine of persons affected with multiple myeloma

Bence–Jones, Henry (1814–1873), British physician. In 1848 Bence-Jones published an article announcing his discovery of a special protein (now known as Bence-Jones protein) in the urine of patients suffering from softening of the bones. The first physician to note the occurrence of xanthine in urine, Bence-Jones was also a recognized authority on diseases of the stomach and kidneys.