hydrochlorothiazide

noun

hy·​dro·​chlo·​ro·​thi·​a·​zide ˌhī-drə-ˌklȯr-ə-ˈthī-ə-ˌzīd 

: a diuretic and antihypertensive drug C₇H₈ClN₃O₄S₂

Examples of hydrochlorothiazide in a Sentence

Recent Examples on the Web

Diuretics like chlorthalidone or hydrochlorothiazide can deplete the body of potassium, magnesium and even sodium. — Joe Graedon, M.s., and Teresa Graedon, Ph.d., oregonlive, 6 Mar. 2023

Common types include thiazide diuretics (like chlorthalidone or hydrochlorothiazide) and loop diuretics (like torsemide or Lasix). — Karen Berger, Verywell Health, 9 Dec. 2025

Examples of diuretic medication include hydrochlorothiazide or furosemide. — Michael Schuh Pharm.d., Anchorage Daily News, 2 Sep. 2023

Bisoprolol fumarate and hydrochlorothiazide tablets made by Glenmark Pharmaceuticals may contain trace amounts of a cholesterol medication. — Jenna Anderson, Health, 9 Dec. 2025

Word History

Etymology

hydr- + chlor- + thiazine + -ide

First Known Use

1958, in the meaning defined above

Rhymes for hydrochlorothiazide

• aminoglycoside
• chlordiazepoxide
• dimethylformamide
• oligosaccharide
• paraformaldehyde
• polynucleotide
• ribonucleotide
• abide
• allied
• applied
• aside
• astride

Medical Definition

hydrochlorothiazide

noun

hy·​dro·​chlo·​ro·​thi·​a·​zide -ˌklōr-ə-ˈthī-ə-ˌzīd, -ˌklȯr- 

: a diuretic and antihypertensive drug C₇H₈ClN₃O₄S₂

—abbreviation HCTZ

Note: Trademarks for preparations containing hydrochlorothiazide include Benicar HCT, Dyazide, Hyzaar, Maxzide, and Tribenzor.