noun \ˈep-ə-ˌsōm, -ˌzōm\

Definition of EPISOME

: a genetic determinant (as the DNA of some bacteriophages) that can replicate either autonomously in bacterial cytoplasm or as an integral part of their chromosomes—compare plasmid
epi·som·al \ˌep-ə-ˈsō-məl, -ˈzō-\ adjective
epi·som·al·ly \-mə-lē\ adverb

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