creatinine

noun

cre·​at·​i·​nine krē-ˈa-tə-ˌnēn 

-ən

: a white crystalline strongly basic compound C₄H₇N₃O formed from creatine and found especially in muscle, blood, and urine

Examples of creatinine in a Sentence

Recent Examples on the Web

White blood cells in urine, high levels of creatinine and low urine volume are often the only clues that alert clinicians to the problem. — Jyoti Madhusoodanan, Scientific American, 17 Mar. 2026

In drug testing, urine creatinine levels are used to help detect urine sample dilution. — Jillian Kubala, Health, 26 Aug. 2025

The testing looked at form factors, creatine per serving, percent creatine, creatinine levels and heavy metals. — Samantha Agate, Kansas City Star, 24 June 2026

Kidney disease when creatinine rises or eGFR drops, sometimes long before symptoms. — Web Golinkin, Forbes.com, 6 May 2026

Word History

Etymology

German Kreatinin, from Kreatin creatine

First Known Use

1847, in the meaning defined above

Rhymes for creatinine

• alkaline
• andesine
• anodyne
• anticline
• arginine
• asinine
• benzidine
• borderline
• byzantine
• calamine
• caroline
• centerline

Medical Definition

creatinine

noun

cre·​at·​i·​nine krē-ˈat-ᵊn-ˌēn, -ᵊn-ən 

: a white crystalline strongly basic compound C₄H₇N₃O formed from creatine and found especially in muscle, blood, and urine