ceramide

noun

cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
ˈser-
plural ceramides
: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids
The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.L. Stivitz
Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web
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The fragrance-free formula nourishes both scalp and lengths, with hyaluronic acid, glycerin, ceramides, and niacinamide working together to hydrate, strengthen, and support a healthier hair environment. Conçetta Ciarlo, Vogue, 30 Oct. 2025 The formula blends niacinamide, essential ceramides, hyaluronic acid, and Centella asiatica extract into a base of luxe shea butter to restore and strengthen the lips’ delicate skin. Christa Joanna Lee, Allure, 25 Oct. 2025 Use the right barrier repair moisturizer Barrier repair moisturizers mimic the 1:1:1 ratio of ceramides, cholesterol and fatty acids found in your skin’s natural barrier to help strengthen, protect and repair it. Leslie Baumann, Miami Herald, 23 Oct. 2025 CeraVe Blemish Barrier Patches are the first and only hydrocolloid blemish patches with three essential ceramides plus niacinamide, helping to soothe the skin while immediately reducing the appearance of all types of blemishes upon application. Adam Mills, MSNBC Newsweek, 15 Oct. 2025 See All Example Sentences for ceramide

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Time Traveler
The first known use of ceramide was in 1958

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Cite this Entry

“Ceramide.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/ceramide. Accessed 3 Nov. 2025.

Medical Definition

ceramide

noun
cer·​amide ˈsir-ə-ˌmīd How to pronounce ceramide (audio)
: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue

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