ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

ˈser-

plural ceramides

: any of various simple sphingolipids that are composed of a fatty acid linked to sphingosine, are found especially in cell membranes, are involved in mediating various cellular processes (such as those affecting cell differentiation and apoptosis), and act as precursors for more complex sphingolipids

The enzyme controls production of a cellular substance, ceramide, which triggers the natural process of egg cell death.

—L. Stivitz

Moisturizers containing ceramides (natural lipids that are similar in structure to those in the skin's own moisture barrier) … are also worthwhile splurges for women with dry or problem skin, according to independent tester Grove.

—Constance Cardozo

Examples of ceramide in a Sentence

Recent Examples on the Web

Antioxidants and ceramides help reduce hair breakage and promote elasticity. — Bestreviews, Mercury News, 7 July 2026

The best products to use after shaving are those that combine hydration with barrier-supporting ingredients such as ceramides, glycerin, hyaluronic acid, colloidal oatmeal, panthenol, and niacinamide. — Emma-Jade Stoddart, Glamour, 5 July 2026

That's why many Korean highlighters blur the line between makeup and skin care, often incorporating ingredients like hyaluronic acid, ceramides, peptides, and squalane to support a dewy-looking complexion. — Christa Joanna Lee, Allure, 6 July 2026

In addition to providing a temporary glow, the formula features skin-benefiting ingredients such as ceramides, vitamin E, and glycerin for long-term benefits, too. — Gina Vaynshteyn, StyleCaster, 30 June 2026

Word History

Etymology

cerebroside + amide

First Known Use

1958, in the meaning defined above

Rhymes for ceramide

• actinide
• aldehyde
• alkoxide
• alongside
• amplified
• arsenide
• beautified
• biocide
• bisulphide
• butoxide
• calcified
• certified

Medical Definition

ceramide

noun

cer·​amide ˈsir-ə-ˌmīd 

: any of a group of amido sphingolipids formed by linking a fatty acid to sphingosine and found widely in small amounts in plant and animal tissue