Definition of tropical sprue
: 2sprue 1
First Known Use of tropical sprue
Medical Definition of tropical sprue
: a disease of tropical regions that is of unknown cause and is characterized by fatty diarrhea, malabsorption of nutrients, and weight loss <Though pathologically indistinguishable from nontropical sprue (i.e., gluten-sensitive enteropathy, or celiac disease), tropical sprue … does not respond to the removal of gluten from the diet …—Edward T. Ryan et al., The New England Journal of Medicine, 15 Aug. 2002>—called also sprue
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