toxicity

noun

tox·​ic·​i·​ty täk-ˈsi-sə-tē 

plural toxicities

: the quality or state of being toxic: such as

a

: the quality, state, or relative degree of being poisonous

measuring the toxicity level of the soil

The toxicity of some chemical agents degrades significantly over time, so it is unclear how lethal the stockpiles are.

—David S. Cloud

Administering a cocktail of drugs would dilute the toxicities of the different drugs and minimize the development of viral resistance to them.

—Rudy M. Baum and Ron Dagani

b

: an extremely harsh, malicious, or harmful quality

In the past few days, I've tuned in to C-SPAN to watch a number of the televised Senate debates, which illustrate all too vividly the toxicity of an uncivil tongue.

—Connie Schultz

In much of the ensuing commentary, court watchers worried that the justices' soaring rates of written dissents, nasty and personal attacks and scathing remarks read aloud from the bench bespeak a new toxicity in Supreme Court discourse.

—Dahlia Lithwick

Did you know?

Toxicity is often a relative thing; in the words of a famous old saying, "The dose makes the poison". Thus, it's possible to die from drinking too much water, and lives have been saved by tiny doses of arsenic. Even though botulinum toxin is the most toxic substance known, it's the basic ingredient in Botox, which is injected into the face to get rid of wrinkles. With some poisons, mere skin contact can be lethal; others are lethal when breathed into the lungs in microscopic amounts. To determine if a chemical will be officially called a poison, researchers often use the "LD50" test: If 50 milligrams of the substance for every kilogram of an animal's body weight results in the death of 50% of test animals, the chemical is a poison. But there are problems with such tests, and toxicity remains a very individual concept.

Examples of toxicity in a Sentence

Recent Examples on the Web

There’s also the risk of secondary toxicity if a mole comes to the surface, dies, and is eaten by a raptor or other predator. —Arricca Elin Sansone, Southern Living, 17 Oct. 2025

Historically, Fortune has featured her at its Most Powerful Women platform to discuss online toxicity, civic engagement, and tech accountability, a thread that continues in coverage of her and Prince Harry’s calls for platform policy changes at Meta. —Sydney Lake, Fortune, 14 Oct. 2025

The documentary pulled back the curtain on one of Taylor Swift's most vulnerable chapters, capturing her reckoning with fame, body image issues and the pressure to please everyone, while also embracing her voice in LGBTQ+ advocacy and confronting online toxicity. —Bryan West, USA Today, 13 Oct. 2025

But during the difficult years, when a horrible cocktail of apathy and toxicity set in, attendance was notably lower. —Amy Lawrence, New York Times, 10 Oct. 2025

Word History

First Known Use

1873, in the meaning defined above

Rhymes for toxicity

• basicity
• chronicity
• complicity
• cyclicity
• duplicity
• ethnicity
• facticity
• felicity
• helicity
• plasticity
• publicity
• rusticity

Medical Definition

toxicity

noun

tox·​ic·​i·​ty täk-ˈsis-ət-ē 

plural toxicities

: the quality, state, or relative degree of being toxic or poisonous