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substance
1 a: essential nature : essence b: a fundamental or characteristic part or quality cChristian Science : god 1b2 a: ultimate reality that underlies all outward manifestations and change b: practical importance : meaning, usefulness <the…bill—which will be without substance in the sense that it will authorize nothing more than a set of ideas
— Richard Reeves>3 a: physical material from which something is made or which has discrete existence b: matter of particular or definite chemical constitution c: something (as drugs or alcoholic beverages) deemed harmful and usually subject to legal restriction <possession of a controlled substance> <substance abuse>4: material possessions : property <a family of substance>
— in substance
: in respect to essentials : fundamentally
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