Papanicolaou smear

noun Pa·pa·ni·co·laou smear \ˌpä-pə-ˈnē-kə-ˌla-, ˌpa-pə-ˈni-\


:  pap smear


George North Papanicolaou †1962 American medical scientist
First Known Use: 1950
Medical Dictionary

Papanicolaou smear

noun Pa·pa·ni·co·laou smear \ˌpäp-ə-ˈnē-kə-ˌla-, ˌpap-ə-ˈnik-ə-\

Medical Definition of PAPANICOLAOU SMEAR

Biographical Note for PAPANICOLAOU SMEAR

Papanicolaou, George Nicholas (1883–1962), American anatomist and cytologist. Papanicolaou devoted his medical research almost entirely to the physiology of reproduction and exfoliative cytology. In 1917 he began studying the vaginal discharge of the guinea pig, examining specifically the histological and physiological changes that occur during a typical estrous cycle. In 1923 he turned to the cytological examination of the vaginal fluid of women as a way of detecting uterine cancer. In 1943 he published his findings after studying 179 cases of uterine cancer. His monograph Diagnosis of Uterine Cancer by Vaginal Smear treated a variety of physiological and pathological states, including abortion, amenorrhea, ectopic pregnancy, endometrial hyperplasia, menopause, the menstrual cycle, prepuberty, and puerperium. The Papanicolaou smear rapidly achieved wide acceptance as a means of cancer diagnosis.


Next Word in the Dictionary: Papanicolaou testPrevious Word in the Dictionary: papaloiAll Words Near: Papanicolaou smear
July 02, 2015
apprehension Hear it
comprehension or the fear of future evil
Take a 3-minute break and test your skills!
How to use a word that (literally) drives some people nuts.
Test your vocab with our fun, fast game
Ailurophobia, and 9 other unusual fears